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The Cardinals take on the Cubs in game one of this rare five-game series tonight at 6:05 pm. Here are the lineups:
| Cardinals | Cubs | ||
| Matt Carpenter | 5 | Anthony Rizzo | 3 |
| Yadier Molina | 2 | Kris Bryant | 5 |
| Paul DeJong | 6 | Jason Heyward | 9 |
| Marcell Ozuna | 7 | Ben Zobrist | 4 |
| Jedd Gyorko | 5 | Ian Happ | 8 |
| Kolten Wong | 4 | Flapjacks | 7 |
| Dexter Fowler | 9 | Addison Russell | 6 |
| Tommy Pham | 8 | Victor Caratini | 2 |
| Carlos Martínez
| 1 | Kyle Hendricks | 1 |
Cardinals record against the Cubs 2018: 5-3
Cardinals record in the series: 0-0
Cardinals place in the NL Central: 3rd
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