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The Cardinals take on the White Sox in game one of this two-game series tonight at 7:10 pm. Here are the lineups:
| Cardinals | White Sox | ||
| Matt Carpenter | 5 | Yoan Moncada | 4 |
| Tommy Pham | 8 | Carlos Sanchez | 5 |
| José Martínez | DH | Jose Abreu | 3 |
| Marcell Ozuna | 7 | Daniel Palka | 7 |
| Yadier Molina | 2 | Matt Davidson | DH |
| Jedd Gyorko | 5 | Leury Garcia | 9 |
| Dexter Fowler | 9 | Omar Narvaez | 2 |
| Paul Dejong | 6 | Tim Anderson | 6 |
Kolten Wong | 4 | Charlie Tilson | 8 |
Pitchers: Miles Mikolas versus Dylan Covey
Cardinals record against White Sox in 2018: 2-0
Cardinals record in the series: 0-0
Cardinals place in the NL Central: 3rd
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