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The Cardinals square off against the Padres for game two of this three-game series this evening at 7:15 pm. Here are the lineups:
| Cardinals | Marlins | ||
| Matt Carpenter | 5 | Travis Jankowski | 7 |
| Tommy Pham | 8 | Eric Hosmer | 3 |
| José Martínez | 3 | Jose Pirela | 4 |
| Marcell Ozuna | 7 | Hunter Renfroe | 9 |
| Yadier Molina | 2 | Cory Spangenberg | 5 |
| Jedd Gyorko | 4 | Freddy Galvis | 6 |
| Harrison Bader | 9 | Manuel Margot | 8 |
| Yairo Muñoz | 6 | A.j. Ellis | 2 |
| Miles Mikolas
| 1 | Matt Strahm | 1 |
Cardinals record against the Padres in 2018: 3-2
Cardinals record in the series: 1-0
Cardinals place in the NL Central: 3rd
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