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The Cardinals square off against the Phillies in this first of four starting this evening at 6:15 pm. Here are the lineups:
| Cardinals | Phillies | ||
| Tommy Pham | 8 | César Hernández | 4 |
| José Martinez | 4 | Aaron Altherr | 9 |
| Paul DeJong | 6 | Odúbel Herrera | 8 |
| Marcell Ozuna | 7 | Rhys Hoskins | 7 |
| Dexter Fowler | 9 | Carlos Santana | 3 |
| Jedd Gyorko | 5 | Maikel Franco | 5 |
| Matt Carpenter | 4 | Scott Kingery | 6 |
| Francisco Peña | 2 | Jorge Alfaro | 2 |
| Luke Weaver | 1 | Vince Velasquez | 1 |
Cardinals record against the Phillies in 2018: 0-0
Cardinals record in the series: 0-0
Cardinals place in the NL Central: 3rd
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