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Here are the lineups as the Cardinals take on the Mets in Citi Field for their Opening Day matchup:
| Cardinals | Mets | ||
| Dexter Fowler | 9 | Brandon Nimmo | 8 |
| Tommy Pham | 8 | Yoenis Céspedes | 7 |
| Matt Carpenter | 5 | Jay Bruce | 9 |
| Marcell Ozuna | 7 | Asdrúbal Cabrera | 4 |
| José Martínez | 3 | Todd Frazier | 5 |
| Yadier Molina | 2 | Adrián González | 4 |
| Paul DeJong | 6 | Kevin Plawecki | 2 |
| Kolten Wong | 4 | Noah Syndergaard | 1 |
| Carlos Martínez | 1 | Amed Rosario | 6 |